Similar Ca(2+)-signaling properties in keratinocytes and in COS-1 cells overexpressing the secretory-pathway Ca(2+)-ATPase SPCA1.

Cell Calcium. 2003 Aug;34(2):157-62. Callewaert G, Parys JB, De Smedt H, Raeymaekers L, Wuytack F, Vanoevelen J, Van Baelen K, Simoni A, Rizzuto R, Missiaen L. Source Laboratorium voor Fysiologie, K U Leuven Campus Gasthuisberg O/N, Herestraat 49, 3000 Leuven, Belgium. Abstract Mutations in the ubiquitously expressed secretory-pathway Ca(2+)-ATPase (SPCA1) … Read More

PMR1/SPCA Ca2+ pumps and the role of the Golgi apparatus as a Ca2+ store.

Pflugers Arch. 2003 May;446(2):148-53. Epub 2003 Feb 15. Wuytack F, Raeymaekers L, Missiaen L. Source Laboratorium voor Fysiologie, K.U. Leuven Campus Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium. frank.wuytack@med.kuleuven.ac.be Abstract Besides the well-known sarco/endoplasmic-reticulum Ca(2+)-transport ATPases (SERCA), animal cells contain a much less characterized … Read More

Abnormal intracellular ca(2+)homeostasis and disease.

Cell Calcium. 2000 Jul;28(1):1-21. Missiaen L, Robberecht W, van den Bosch L, Callewaert G, Parys JB, Wuytack F, Raeymaekers L, Nilius B, Eggermont J, De Smedt H. Source Laboratory of Physiology, K.U.Leuven Campus Gasthuisberg O/N, Leuven, Belgium. Ludwig.Missiaen@med.kuleven.ac.be Abstract A whole range of cell functions are regulated by the free … Read More

Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.

Hum Mol Genet. 2000 Apr 12;9(7):1131-40. Sudbrak R, Brown J, Dobson-Stone C, Carter S, Ramser J, White J, Healy E, Dissanayake M, Larrègue M, Perrussel M, Lehrach H, Munro CS, Strachan T,Burge S, Hovnanian A, Monaco AP. Source Max-Planck-Institut für Molekulare Genetik, D-14195 Berlin, Germany. Abstract Hailey-Hailey disease (HHD) is an autosomal dominant skin disorder … Read More